RAF Typhoon FGR4s have conducted a mission with France's air force in a combined operation on an hidden munitions depot in Syria used by the Daesh militant organization, per a report from the UK Ministry of Defence.
The site, pinpointed through intelligence, was assessed as containing munitions and bombs, the release indicated, and was located in mountainous terrain just above the ancient city of Palmyra in the heart of Syria.
"Our aircraft employed laser-guided Paveway IV weapons to hit a series of entry passages down to the depot... initial indications are that the objective was successfully hit," the MoD said.
There was no sign of any harm to civilians in the strike late on Saturday and every plane involved returned to base without incident, the ministry further stated.
The British jets were supported by a Voyager refuelling tanker.
Daesh - also known as the so-called Islamic State - enforced jihadist rule over large swathes of Iraq and Syria before its territorial defeat in 2019.
"This operation demonstrates British leadership, and commitment to operate in unison with our allies, to eliminate any re-emergence of IS and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief the minister stated.
RAF aircraft have conducted patrols over Syria to "deter any efforts to regroup" of IS after its military defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I extend gratitude to the personnel of our armed forces involved in this operation for their skill and their valour," Healey said. "They were part of numerous British personnel on duty over the festive period. This mission, to eliminate terrorist threats who threaten our safety, highlights how UK forces are always on standby, continuously, protecting the UK at home and strong abroad."
Last December, the American forces conducted what it termed a "large-scale strike" targeting Islamic State objectives in the country, subsequent to an ambush killed two US troops and a local interpreter in Palmyra.
The United Nations says Islamic State still maintains between 5,000 and 7,000 militants in Syria and Iraq.